DNP-NH-PEG2-C2-acid


Catalog No. Size PriceQuantity
M26959-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

DNP-NH-PEG2-C2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Product information

CAS Number: 1353011-89-8

Molecular Weight: 343.29

Formula: C13H17N3O8

Chemical Name: 3-(2-{2-[(2,4-dinitrophenyl)amino]ethoxy}ethoxy)propanoic acid

Smiles: [O-][N+](=O)C1=CC(=CC=C1NCCOCCOCCC(O)=O)[N+]([O-])=O

InChiKey: ZZALENBFHFRJPM-UHFFFAOYSA-N

InChi: InChI=1S/C13H17N3O8/c17-13(18)3-5-23-7-8-24-6-4-14-11-2-1-10(15(19)20)9-12(11)16(21)22/h1-2,9,14H,3-8H2,(H,17,18)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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