Ac4GalNAl


Catalog No. Size PriceQuantity
M26988-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Ac4GalNAl is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1673590-09-4

Molecular Weight: 427.40

Formula: C19H25NO10

Chemical Name: [(2R,3R,4R,5R,6S)-3,4,6-tris(acetyloxy)-5-(pent-4-ynamido)oxan-2-yl]methyl acetate

Smiles: CC(=O)O[C@H]1[C@@H](OC(C)=O)[C@@H](COC(C)=O)O[C@@H](OC(C)=O)[C@@H]1NC(=O)CCC#C

InChiKey: PODQGPKRSTUNAT-IQZDNPOKSA-N

InChi: InChI=1S/C19H25NO10/c1-6-7-8-15(25)20-16-18(28-12(4)23)17(27-11(3)22)14(9-26-10(2)21)30-19(16)29-13(5)24/h1,14,16-19H,7-9H2,2-5H3,(H,20,25)/t14-,16-,17+,18-,19-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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