Description
PPC-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Product information
CAS Number: 107348-47-0
Molecular Weight: 326.39
Formula: C13H14N2O4S2
Chemical Name: 2,5-dioxopyrrolidin-1-yl 3-(pyridin-2-yldisulfanyl)butanoate
Smiles: CC(CC(=O)ON1C(=O)CCC1=O)SSC1=CC=CC=N1
InChiKey: VQZYZXLBKBUOHE-UHFFFAOYSA-N
InChi: InChI=1S/C13H14N2O4S2/c1-9(20-21-10-4-2-3-7-14-10)8-13(18)19-15-11(16)5-6-12(15)17/h2-4,7,9H,5-6,8H2,1H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Products are for research use only. Not for human use.
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