Description
16-Keto Aspergillimide (SB202327) is an anthelmintic agent isolated from Aspergillus strain IMI 337664.
Product information
CAS Number: 199784-50-4
Molecular Weight: 373.45
Formula: C20H27N3O4
Chemical Name: (3S,3'S,7'S,12'S)-1,4',4',12',14'-pentamethyl-9',14'-diazaspiro[pyrrolidine-3,5'-tetracyclo[5.5.2.0¹,⁹.0³,⁷]tetradecane]-2,5,10',13'-tetrone
Smiles: CC1(C)[C@@H]2CC34[C@@H](C)CC(=O)N3C[C@@]2(C[C@@]21CC(=O)N(C)C2=O)N(C)C4=O
InChiKey: YAYKUKWEFJDSJG-SMEOYISOSA-N
InChi: InChI=1S/C20H27N3O4/c1-11-6-13(24)23-10-19-9-18(8-14(25)21(4)15(18)26)17(2,3)12(19)7-20(11,23)16(27)22(19)5/h11-12H,6-10H2,1-5H3/t11-,12-,18-,19+,20?/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
The oral activities of 16-Keto Aspergillimide (SB202327) against adult Trichostrongylus colubriformis infections in gerbils are determined. During bioassay-guided extraction (Haemonchus contortus L3 larvae), the 16-Keto Aspergillimide (SB202327) shows evidence of activity in vitro but not in vivo.
Products are for research use only. Not for human use.
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