Description
Imirestat (AL 1576) is an aldose reductase inhibitor, used for the treatment of diabetes.
Product information
CAS Number: 89391-50-4
Molecular Weight: 286.23
Formula: C15H8F2N2O2
Chemical Name: 2,7-difluorospiro[fluorene-9,4'-imidazolidine]-2',5'-dione
Smiles: O=C1NC(=O)C2(N1)C1=CC(F)=CC=C1C1=CC=C(F)C=C21
InChiKey: QCCHBHSAIQIQGO-UHFFFAOYSA-N
InChi: InChI=1S/C15H8F2N2O2/c16-7-1-3-9-10-4-2-8(17)6-12(10)15(11(9)5-7)13(20)18-14(21)19-15/h1-6H,(H2,18,19,20,21)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 83.33 mg/mL (291.13 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vivo:
Imirestat (1 mg/kg) improves nerve conduction velocity but is without effect upon the resistance to hypoxic conduction blockade or the deficit in insulin-stimulated oubain-sensitive ATPase activity.
Products are for research use only. Not for human use.
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