Description
Cyclo(RADfK) is a selective α(v)β(3) integrin ligand that has been extensively used for research, therapy, and diagnosis of neoangiogenesis.
Product information
CAS Number: 756500-23-9
Molecular Weight: 617.70
Formula: C28H43N9O7
Chemical Name: 2-[(2R,5R,8S,11S,14S)-8-(4-aminobutyl)-5-benzyl-11-{3-[(diaminomethylidene)amino]propyl}-14-methyl-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaazacyclopentadecan-2-yl]acetic acid
Smiles: C[C@@H]1NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](CC2C=CC=CC=2)NC(=O)[C@@H](CC(O)=O)NC1=O
InChiKey: SMFHXHGBDFBWOX-OFOKGCAXSA-N
InChi: InChI=1S/C28H43N9O7/c1-16-23(40)36-21(15-22(38)39)27(44)37-20(14-17-8-3-2-4-9-17)26(43)35-18(10-5-6-12-29)25(42)34-19(24(41)33-16)11-7-13-32-28(30)31/h2-4,8-9,16,18-21H,5-7,10-15,29H2,1H3,(H,33,41)(H,34,42)(H,35,43)(H,36,40)(H,37,44)(H,38,39)(H4,30,31,32)/t16-,18-,19-,20+,21+/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: H2O : 100 mg/mL (161.89 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Cyclo(RADfK) is a negative control for the cyclo (-RGDfK-), the RGD peptide. RGD peptides are modulators of cell adhesion and are recognized by several members of the integrin family.
Products are for research use only. Not for human use.
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