Prifuroline


Catalog No. Size PriceQuantity
M27199-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Prifuroline is an antiarrhythmic agent.

Product information

CAS Number: 70833-07-7

Molecular Weight: 228.29

Formula: C14H16N2O

Chemical Name: 3-(1-benzofuran-2-yl)-N,N-dimethyl-3,4-dihydro-2H-pyrrol-5-amine

Smiles: CN(C)C1CC(CN=1)C1=CC2=CC=CC=C2O1

InChiKey: IYMLHOSZPZHXCR-UHFFFAOYSA-N

InChi: InChI=1S/C14H16N2O/c1-16(2)14-8-11(9-15-14)13-7-10-5-3-4-6-12(10)17-13/h3-7,11H,8-9H2,1-2H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

Prifuroline is an antiarrhythmic agent. Prifuroline dose-dependently antagonizes the arrhythmogenic action of aconitine in rats, when administered either intravenously (5, 10 or 20 mg/kg) or intraduodenally (10, 20 or 50 mg/kg). Prifuroline also diminishes ventricular susceptibility to electrical stimulation in open-chest rats. The arrhythmias induced in dogs by coronary artery ligation are markedly antagonized by Prifuroline after doses of 5 and 10 mg/kg i.v. or 30 mg/kg intraduodenally. The duration of its antiarrhythmic activity in this model of arrhythmias in conscious dogs is much longer after intraduodenal than after i.v. administration.

Products are for research use only. Not for human use.

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