EGTA-AM


Catalog No. Size PriceQuantity
M27253-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

EGTA-AM is a membrane permeable form of EGTA, can be passively loaded into cells to generate intracellular EGTA; EGTA-AM is also a Ca2+ chelator with slow chelating dynamics.

Product information

CAS Number: 99590-86-0

Molecular Weight: 668.60

Formula: C26H40N2O18

Chemical Name: 1,14-di(acetyloxy)methyl 3,12-bis({2-[(acetyloxy)methoxy]-2-oxoethyl})-6,9-dioxa-3,12-diazatetradecanedioate

Smiles: CC(=O)OCOC(=O)CN(CC(=O)OCOC(C)=O)CCOCCOCCN(CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O

InChiKey: GNJXVFXIDHCCKR-UHFFFAOYSA-N

InChi: InChI=1S/C26H40N2O18/c1-19(29)39-15-43-23(33)11-27(12-24(34)44-16-40-20(2)30)5-7-37-9-10-38-8-6-28(13-25(35)45-17-41-21(3)31)14-26(36)46-18-42-22(4)32/h5-18H2,1-4H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 50 mg/mL (74.78 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

EGTA-AM (50 μM) markedly reduces the asynchronous excitatory postsynaptic currents (aEPSC) to 58.9 ± 8.1% of the control level, but only reduces the synchronous excitatory postsynaptic currents (EPSCs), measured as charge transfer produced by the stimulation train.

Products are for research use only. Not for human use.

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