Di-8-ANEPPS


Catalog No. Size PriceQuantity
M27270-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Di-8-ANEPPS is a naphthylstyryl voltage-sensitive dye, shifting both their fluorescence excitation and emission spectra upon changes in Vm .

Product information

CAS Number: 157134-53-7

Molecular Weight: 592.87

Formula: C36H52N2O3S

Chemical Name: 4-[(E)-2-[6-(dioctylamino)naphthalen-2-yl]ethenyl]-1-(3-sulfonatopropyl)pyridin-1-ium

Smiles: CCCCCCCCN(CCCCCCCC)C1=CC2=CC=C(C=C2C=C1)/C=C/C1C=C[N+](CCCS([O-])(=O)=O)=CC=1

InChiKey: IXFSUSNUALIXLU-UHFFFAOYSA-N

InChi: InChI=1S/C36H52N2O3S/c1-3-5-7-9-11-13-25-38(26-14-12-10-8-6-4-2)36-21-20-34-30-33(18-19-35(34)31-36)17-16-32-22-27-37(28-23-32)24-15-29-42(39,40)41/h16-23,27-28,30-31H,3-15,24-26,29H2,1-2H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

A mouse cell staining with Di-8-ANEPPS is applied voltage clamp pulses and immersed in Na+-containing solution. The Di-8-ANEPPS signal, which largely reflects t system voltage, has an asymmetrical positive component upon application of depolarizing pulses. This is interpreted as reflecting a propagating action potential, escaping from the voltage-clamped plasma membrane. Its temporal properties are not unlike those of the “center” signal. Notably, the peak of the signal occurrs 0.3 ms after the leading edge of the depolarizing pulse.

Products are for research use only. Not for human use.

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