Apovincamine


Catalog No. Size PriceQuantity
M27330-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Apovincamine (cis-Apovincamine) is an indole alkaloid isolated from the Malaysian Alstonia pneumatophora (Apocynaceae). Apovincamine shows anti-melanogenesis activity.

Product information

CAS Number: 4880-92-6

Molecular Weight: 336.43

Formula: C21H24N2O2

Chemical Name: methyl (15S,19S)-15-ethyl-1,11-diazapentacyclo[9.6.2.0²,⁷.0⁸,¹⁸.0¹⁵,¹⁹]nonadeca-2,4,6,8(18),16-pentaene-17-carboxylate

Smiles: CC[C@@]12CCCN3CCC4=C([C@H]13)N(C(=C2)C(=O)OC)C1=CC=CC=C41

InChiKey: OZDNDGXASTWERN-CTNGQTDRSA-N

InChi: InChI=1S/C21H24N2O2/c1-3-21-10-6-11-22-12-9-15-14-7-4-5-8-16(14)23(18(15)19(21)22)17(13-21)20(24)25-2/h4-5,7-8,13,19H,3,6,9-12H2,1-2H3/t19-,21+/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Apovincamine (cis-Apovincamine; 6.3, 12.5, 25, 50, 100 μM) dose-dependently inhibits cells viability with an IC50 of 49.8 μM and shows anti-melanogenesis in B16 mouse melanoma cells.

Products are for research use only. Not for human use.

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