DS28120313


Catalog No. Size PriceQuantity
M27385-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

DS28120313 (compound 32) is an orally hepcidin production inhibitor with an IC50 of 0.093 μM.

Product information

CAS Number: 2146177-09-3

Molecular Weight: 311.34

Formula: C16H17N5O2

Chemical Name: methyl N-[6-(3-cyclopropyl-5-methyl-1H-pyrazol-4-yl)-1H-indazol-4-yl]carbamate

Smiles: CC1NN=C(C2CC2)C=1C1C=C2NN=CC2=C(C=1)NC(=O)OC

InChiKey: QTYLFQMDDFBRTJ-UHFFFAOYSA-N

InChi: InChI=1S/C16H17N5O2/c1-8-14(15(21-19-8)9-3-4-9)10-5-12(18-16(22)23-2)11-7-17-20-13(11)6-10/h5-7,9H,3-4H2,1-2H3,(H,17,20)(H,18,22)(H,19,21)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

DS28120313 (deliver orally; 30 mg/kg; 30 min before IL-6 administration) inhibits hepcidin production and reduces the blood hepcidin level in IL-6 induced acute inflammatory C57BL/6 mouse model.

Products are for research use only. Not for human use.

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