Description
Paeoniflorigenone, isolated as an active ingredient from the root of moutan cortex, induces apoptosis selectively in the cancer cell lines and exhibits antiproliferative effect.
Product information
CAS Number: 80454-42-8
Molecular Weight: 318.32
Formula: C17H18O6
Chemical Name: [(1S,3R,6S,8S,10S)-8-hydroxy-3-methyl-5-oxo-2,9-dioxatricyclo[4.3.1.0³,⁸]decan-10-yl]methyl benzoate
Smiles: C[C@@]12CC(=O)[C@H]3C[C@]1(O)O[C@H](O2)[C@@H]3COC(=O)C1C=CC=CC=1
InChiKey: BANPEMKDTXIFRE-GMKCAIKYSA-N
InChi: InChI=1S/C17H18O6/c1-16-8-13(18)11-7-17(16,20)23-15(22-16)12(11)9-21-14(19)10-5-3-2-4-6-10/h2-6,11-12,15,20H,7-9H2,1H3/t11-,12+,15-,16+,17-/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Paeoniflorigenone (0-30 μM; 0-72 hours) significantly decreases the cell proliferation of tumor cell lines and inhibits the proliferation of normal cell lines. Paeoniflorigenone (0-30 μM; 24-72 hours) significantly induces apoptotic DNA fragmentation selectively in tumor cells.
Products are for research use only. Not for human use.
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