Pimpinellin


Catalog No. Size PriceQuantity
M27735-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Pimpinellin is a constituent of Cyrtomium fortumei (J.). Pimpinellin inhibits the growth of tumor cells via the induction of tumor cell apoptosis.

Product information

CAS Number: 131-12-4

Molecular Weight: 246.22

Formula: C13H10O5

Chemical Name: 5,6-dimethoxy-2H-furo[2,3-h]chromen-2-one

Smiles: COC1=C(OC)C2OC=CC=2C2OC(=O)C=CC=21

InChiKey: BQPRWZCEKZLBHL-UHFFFAOYSA-N

InChi: InChI=1S/C13H10O5/c1-15-11-7-3-4-9(14)18-10(7)8-5-6-17-12(8)13(11)16-2/h3-6H,1-2H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 100 mg/mL (406.14 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Pimpinellin has potent cytotoxic activities against the three tumor cells MGC-803, PC3, and A375, with the IC50 values of 14.4±0.3 μM, 20.4±0.5 μM, and 29.2±0.6 μM, respectively. Pimpinellin inhibits the growth of MGC-803 cells via the induction of tumor cell apoptosis, with apoptosis ratio of 27.44% after 72 h of treatment at 20 μM.

Products are for research use only. Not for human use.

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