AOH1160


Catalog No. Size PriceQuantity
M27757-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

AOH1160 is a potent, first-in-class, orally available small molecule proliferating cell nuclear antigen (PCNA) inhibitor, interferes with DNA replication, blocks homologous recombination-mediated DNA repair, causes cell-cycle arrest and induces apoptosis. AOH1160 selectively kills many types of cancer cells (mean GI50=330 nM) without causing significant toxicity to a broad range of nonmalignant cells.

Product information

CAS Number: 2089314-57-6

Molecular Weight: 396.44

Formula: C25H20N2O3

Chemical Name: 2-[(naphthalen-1-yl)formamido]-N-(2-phenoxyphenyl)acetamide

Smiles: O=C(NCC(=O)NC1=CC=CC=C1OC1C=CC=CC=1)C1=CC=CC2=CC=CC=C21

InChiKey: COPRLRLXDBSLET-UHFFFAOYSA-N

InChi: InChI=1S/C25H20N2O3/c28-24(17-26-25(29)21-14-8-10-18-9-4-5-13-20(18)21)27-22-15-6-7-16-23(22)30-19-11-2-1-3-12-19/h1-16H,17H2,(H,26,29)(H,27,28)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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