Abemaciclib metabolite M2


Catalog No. Size PriceQuantity
M27789-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Abemaciclib metabolite M2 (LSN2839567) is a metabolite of Abemaciclib, acts as a potent CDK4 and CDK6 inhibitor, with IC50s in the range of 1-3 nM. Anti-cancer activity.

Product information

CAS Number: 1231930-57-6

Molecular Weight: 478.54

Formula: C25H28F2N8

Chemical Name: 5-fluoro-4-[4-fluoro-2-methyl-1-(propan-2-yl)-1H-1,3-benzodiazol-6-yl]-N-{5-[(piperazin-1-yl)methyl]pyridin-2-yl}pyrimidin-2-amine

Smiles: CC1=NC2=C(C=C(C=C2F)C2=NC(NC3=CC=C(CN4CCNCC4)C=N3)=NC=C2F)N1C(C)C

InChiKey: IXGZDCRFGCEEBU-UHFFFAOYSA-N

InChi: InChI=1S/C25H28F2N8/c1-15(2)35-16(3)31-24-19(26)10-18(11-21(24)35)23-20(27)13-30-25(33-23)32-22-5-4-17(12-29-22)14-34-8-6-28-7-9-34/h4-5,10-13,15,28H,6-9,14H2,1-3H3,(H,29,30,32,33)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 2 mg/mL (4.18 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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