GPI-1485


Catalog No. Size PriceQuantity
M27871-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

GPI-1485 (GM1485), a nonimmunosuppressive immunophilin ligand, promotes neurofunctional improvement and neural regeneration following stroke.

Product information

CAS Number: 186268-78-0

Molecular Weight: 241.28

Formula: C12H19NO4

Chemical Name: (2S)-1-(3,3-dimethyl-2-oxopentanoyl)pyrrolidine-2-carboxylic acid

Smiles: CCC(C)(C)C(=O)C(=O)N1CCC[C@H]1C(O)=O

InChiKey: FOPALECPEUVCTL-QMMMGPOBSA-N

InChi: InChI=1S/C12H19NO4/c1-4-12(2,3)9(14)10(15)13-7-5-6-8(13)11(16)17/h8H,4-7H2,1-3H3,(H,16,17)/t8-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 100 mg/mL (414.46 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

GPI-1485 (GM1485; 100 μM) induces cellular reprogramming and neural cell induction in normal human dermal fibroblasts (NHDF).

In Vivo:

GPI-1485 (GM1485; 5 mg/kg; intraperitoneal injection; 6-week period of daily) improves long-term neurological recovery in rats.

Products are for research use only. Not for human use.

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