Description
RU-302 is a pan TAM inhibitor that blocks the interface between the TAM Ig1 ectodomain and the Gas6 Lg domain. RU-302 effectively blocks Gas6-inducible Axl receptor activation with a low micromolar IC50in cell assays, and suppresses lung cancer tumor growth.
Product information
CAS Number: 1182129-77-6
Molecular Weight: 475.53
Formula: C24H24F3N3O2S
Chemical Name: 1-(2-{[(3,5-dimethyl-1,2-oxazol-4-yl)methyl]sulfanyl}benzoyl)-4-[3-(trifluoromethyl)phenyl]piperazine
Smiles: CC1ON=C(C)C=1CSC1=CC=CC=C1C(=O)N1CCN(CC1)C1=CC(=CC=C1)C(F)(F)F
InChiKey: IZHRNXCFYZERFF-UHFFFAOYSA-N
InChi: InChI=1S/C24H24F3N3O2S/c1-16-21(17(2)32-28-16)15-33-22-9-4-3-8-20(22)23(31)30-12-10-29(11-13-30)19-7-5-6-18(14-19)24(25,26)27/h3-9,14H,10-13,15H2,1-2H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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