HBDDE


Catalog No. Size PriceQuantity
M27946-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

HBDDE, a derivative of Ellagic acid, is an isoform-selective PKCα and PKCγ inhibitor with IC50s of 43 μM and 50 μM, respectively. HBDDE shows selective for PKCα/PKCγ over PKCδ, PKCβI and PKCβII isozymes. HBDDE induces neuronal apoptosis.

Product information

CAS Number: 154675-18-0

Molecular Weight: 338.31

Formula: C16H18O8

Chemical Name: 6,6'-bis(methoxymethyl)-[1,1'-biphenyl]-2,2',3,3',4,4'-hexol

Smiles: COCC1=CC(O)=C(O)C(O)=C1C1=C(COC)C=C(O)C(O)=C1O

InChiKey: NEBCAMAQXZIVRE-UHFFFAOYSA-N

InChi: InChI=1S/C16H18O8/c1-23-5-7-3-9(17)13(19)15(21)11(7)12-8(6-24-2)4-10(18)14(20)16(12)22/h3-4,17-22H,5-6H2,1-2H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

HBDDE (50 μM; 5 hours) treatment reduces cell viability significantly by ~70%. HBDDE exhibits a marked increase in caspase-3 activity.

Products are for research use only. Not for human use.

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