HIF-2α-IN-2


Catalog No. Size PriceQuantity
M28103-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

HIF-2α-IN-2 is a hypoxia-inducible factors (HIF-2α) inhibitor extracted from patent WO2015035223A1, Compound 232, has an IC50 of 16 nM in scintillation proximity assay (SPA).

Product information

CAS Number: 1672666-82-8

Molecular Weight: 365.35

Formula: C17H13F2NO4S

Chemical Name: 3-fluoro-5-[(2-fluoro-1-hydroxy-7-methanesulfonyl-2,3-dihydro-1H-inden-4-yl)oxy]benzonitrile

Smiles: CS(=O)(=O)C1=CC=C(OC2C=C(F)C=C(C=2)C#N)C2CC(F)C(O)C1=2

InChiKey: GTHLUQQEKIJSME-UHFFFAOYSA-N

InChi: InChI=1S/C17H13F2NO4S/c1-25(22,23)15-3-2-14(12-7-13(19)17(21)16(12)15)24-11-5-9(8-20)4-10(18)6-11/h2-6,13,17,21H,7H2,1H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 100 mg/mL (273.71 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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