Description
Silver sulfadiazine (AgSD), a sulfonamide antibiotic, effects a dual inhibitory action on bacterial growth by its sulfa moiety (SD-SDZ) that prevents bacterial folate absorption and subsequent DNA synthesis. The silver that is released from Silver sulfadiazine binds and disrupts the DNA structure, precluding bacterial DNA replication.
Product information
CAS Number: 22199-08-2
Molecular Weight: 357.14
Formula: C10H9AgN4O2S
Chemical Name: silver(1+) 4-{[(pyrimidin-2-yl)azanidyl]sulfonyl}aniline
Smiles: [Ag+].NC1C=CC(=CC=1)S(=O)(=O)[N-]C1N=CC=CN=1
InChiKey: UEJSSZHHYBHCEL-UHFFFAOYSA-N
InChi: InChI=1S/C10H9N4O2S.Ag/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10;/h1-7H,11H2;/q-1;+1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : < 1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble or slightly soluble).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Silver sulfadiazine (AgSD) is a topical antibiotic used to the research of bacterial infection in burns.
Products are for research use only. Not for human use.
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