SORT-PGRN interaction inhibitor 1


Catalog No. Size PriceQuantity
M28187-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

SORT-PGRN interaction inhibitor 1 is a potent inhibitor of the sortilin-progranulin interaction with an IC50 of 2 μM.

Product information

CAS Number: 100957-85-5

Molecular Weight: 258.32

Formula: C15H18N2O2

Chemical Name: 1-benzyl-3-tert-butyl-1H-pyrazole-5-carboxylic acid

Smiles: CC(C)(C)C1C=C(C(O)=O)N(CC2C=CC=CC=2)N=1

InChiKey: IJXYLILRNVOJNF-UHFFFAOYSA-N

InChi: InChI=1S/C15H18N2O2/c1-15(2,3)13-9-12(14(18)19)17(16-13)10-11-7-5-4-6-8-11/h4-9H,10H2,1-3H3,(H,18,19)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 100 mg/mL (387.12 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

SORT-PGRN interaction inhibitor 1 (Compound 2) with sufficient potency and physicochemical properties to enable co-crystallization with sortilin.

Products are for research use only. Not for human use.

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