Description
ROS tracer precursor is the precursor of [18F]ROStrace for the synthesis of ROStrace, which can be used for disease diagnosis.
Product information
CAS Number: 2153480-20-5
Molecular Weight: 715.85
Formula: C39H45N3O8S
Chemical Name: tert-butyl N-(3-{[(tert-butoxy)carbonyl]amino}-5-methyl-6-(4-{2-[(4-methylbenzenesulfonyl)oxy]ethoxy}phenyl)-5,6-dihydrophenanthridin-8-yl)carbamate
Smiles: CC1C=CC(=CC=1)S(=O)(=O)OCCOC1C=CC(=CC=1)C1C2=CC(=CC=C2C2=CC=C(C=C2N1C)NC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C
InChiKey: PVAWZLJBKPGCNK-UHFFFAOYSA-N
InChi: InChI=1S/C39H45N3O8S/c1-25-9-17-30(18-10-25)51(45,46)48-22-21-47-29-15-11-26(12-16-29)35-33-23-27(40-36(43)49-38(2,3)4)13-19-31(33)32-20-14-28(24-34(32)42(35)8)41-37(44)50-39(5,6)7/h9-20,23-24,35H,21-22H2,1-8H3,(H,40,43)(H,41,44)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vivo:
[18F]ROStrace is a radiotracer for imaging superoxide in vivo with positron emission tomography (PET), in an LPS model of neuroinflammation. [18F]ROStrace is found to rapidly cross the blood-brain barrier (BBB) and is trapped in the brain of LPS-treated animals. [18F]ox-ROStrace, the oxidized form of [18F]ROStrace, does not cross the BBB. [18F]ROStrace is a suitable radiotracer for imaging superoxide levels in the central nervous system with PET.
Products are for research use only. Not for human use.
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