Cdc7-IN-1


Catalog No. Size PriceQuantity
M28437-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Cdc7-IN-1 (Compound 13) is a highly potent, selective and ATP competitive inhibitor of Cdc7 kinase, with an IC50 value of 0.6 nM at 1 mM ATP and with slow off-rate characteristics. Cdc7-IN-1 potently inhibits Cdc7 activity in cancer cells, and effectively induces cell death.

Product information

CAS Number: 1402055-25-7

Molecular Weight: 409.82

Formula: C21H16ClN3O4

Chemical Name: ethyl 2-[(2-chlorophenyl)amino]-4-hydroxy-5-{[(3Z)-3H-pyrrolo[2,3-b]pyridin-3-ylidene]methyl}furan-3-carboxylate

Smiles: CCOC(=O)C1C(O)=C(/C=C2\C=NC3=NC=CC=C\23)OC=1NC1=CC=CC=C1Cl

InChiKey: MNEODYFHQBZJNQ-ZRDIBKRKSA-N

InChi: InChI=1S/C21H16ClN3O4/c1-2-28-21(27)17-18(26)16(10-12-11-24-19-13(12)6-5-9-23-19)29-20(17)25-15-8-4-3-7-14(15)22/h3-11,25-26H,2H2,1H3/b12-10+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 5.2 mg/mL (12.69 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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