Bis-(m-PEG4)-amidohexanoic acid


Catalog No. Size PriceQuantity
M28518-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Bis-(m-PEG4)-amidohexanoic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2353409-74-0

Molecular Weight: 582.68

Formula: C26H50N2O12

Chemical Name: (2R)-2,6-bis(2,5,8,11-tetraoxatetradecan-14-amido)hexanoic acid

Smiles: COCCOCCOCCOCCC(=O)NCCCC[C@@H](NC(=O)CCOCCOCCOCCOC)C(O)=O

InChiKey: VEMVVACPIWNZPA-HSZRJFAPSA-N

InChi: InChI=1S/C26H50N2O12/c1-33-11-13-37-19-21-39-17-15-35-9-6-24(29)27-8-4-3-5-23(26(31)32)28-25(30)7-10-36-16-18-40-22-20-38-14-12-34-2/h23H,3-22H2,1-2H3,(H,27,29)(H,28,30)(H,31,32)/t23-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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