Azido-PEG2-azide


Catalog No. Size PriceQuantity
M28527-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Azido-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 59559-06-7

Molecular Weight: 200.20

Formula: C6H12N6O2

Chemical Name: 1-azido-2-[2-(2-azidoethoxy)ethoxy]ethane

Smiles: [N-]=[N+]=NCCOCCOCCN=[N+]=[N-]

InChiKey: OHZGAFKSAANFAS-UHFFFAOYSA-N

InChi: InChI=1S/C6H12N6O2/c7-11-9-1-3-13-5-6-14-4-2-10-12-8/h1-6H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 100 mg/mL (499.50 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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