Description
APN-NH2 is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 1539292-61-9
Molecular Weight: 227.26
Formula: C13H13N3O
Chemical Name: 4-amino-N-[4-(2-cyanoeth-1-yn-1-yl)phenyl]butanamide
Smiles: NCCCC(=O)NC1C=CC(=CC=1)C#CC#N
InChiKey: RLTVJTXRTMTNBC-UHFFFAOYSA-N
InChi: InChI=1S/C13H13N3O/c14-9-1-3-11-5-7-12(8-6-11)16-13(17)4-2-10-15/h5-8H,2,4,10,15H2,(H,16,17)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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