Diketone-PEG4-PFP ester


Catalog No. Size PriceQuantity
M28620-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Diketone-PEG4-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2353409-84-2

Molecular Weight: 647.58

Formula: C30H34F5NO9

Chemical Name: 2,3,4,5,6-pentafluorophenyl 1-{[4-(3,5-dioxohexyl)phenyl]carbamoyl}-3,6,9,12-tetraoxapentadecan-15-oate

Smiles: CC(=O)CC(=O)CCC1C=CC(=CC=1)NC(=O)CCOCCOCCOCCOCCC(=O)OC1C(F)=C(F)C(F)=C(F)C=1F

InChiKey: YJNZZHGXYBSDRO-UHFFFAOYSA-N

InChi: InChI=1S/C30H34F5NO9/c1-19(37)18-22(38)7-4-20-2-5-21(6-3-20)36-23(39)8-10-41-12-14-43-16-17-44-15-13-42-11-9-24(40)45-30-28(34)26(32)25(31)27(33)29(30)35/h2-3,5-6H,4,7-18H2,1H3,(H,36,39)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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