Indirubin Derivative E804


Catalog No. Size PriceQuantity
M28621-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Indirubin Derivative E804 is a potent inhibitor of Insulin-like Growth Factor 1 Receptor (IGF1R), with an IC50 of 0.65 μM for IGF1R.

Product information

CAS Number: 854171-35-0

Molecular Weight: 365.38

Formula: C20H19N3O4

Chemical Name: 4-({[(3Z)-2'-hydroxy-1'H,3H-[2,3'-biindol]-3-ylidene]amino}oxy)butane-1,2-diol

Smiles: OC1NC2=CC=CC=C2C=1C1=NC2=CC=CC=C2/C/1=N/OCCC(O)CO

InChiKey: TWOSIFOFWWXXIG-NKFKGCMQSA-N

InChi: InChI=1S/C20H19N3O4/c24-11-12(25)9-10-27-23-18-14-6-2-4-8-16(14)21-19(18)17-13-5-1-3-7-15(13)22-20(17)26/h1-8,12,22,24-26H,9-11H2/b23-18-

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 125 mg/mL (342.11 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Indirubin Derivative E804 is a water-soluble indirubin derivative as potent inhibitor of Insulin-like Growth Factor 1 Receptor (IGF1R), with an IC50 of 0.65 μM. Indirubin Derivative E804 also inhibits CDK2/CycE with an EC50 of 0.23 μM.

Products are for research use only. Not for human use.

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