2-Bromo-2, 2-dimethyl-acetamido-PEG3-acid


Catalog No. Size PriceQuantity
M28639-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

2-Bromo-22-dimethyl-acetamido-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2279944-67-9

Molecular Weight: 370.24

Formula: C13H24BrNO6

Chemical Name: 3-(2-{2-[2-(2-bromo-2-methylpropanamido)ethoxy]ethoxy}ethoxy)propanoic acid

Smiles: CC(C)(Br)C(=O)NCCOCCOCCOCCC(O)=O

InChiKey: CLVVTFBUUWMQLQ-UHFFFAOYSA-N

InChi: InChI=1S/C13H24BrNO6/c1-13(2,14)12(18)15-4-6-20-8-10-21-9-7-19-5-3-11(16)17/h3-10H2,1-2H3,(H,15,18)(H,16,17)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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