Azido-PEG3-S-PEG4-propargyl


Catalog No. Size PriceQuantity
M28677-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Azido-PEG3-S-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2055041-24-0

Molecular Weight: 449.56

Formula: C19H35N3O7S

Chemical Name: 1-azido-3,6,9,15,18,21,24-heptaoxa-12-thiaheptacos-26-yne

Smiles: C#CCOCCOCCOCCOCCSCCOCCOCCOCCN=[N+]=[N-]

InChiKey: WWUGRHVDODLKCE-UHFFFAOYSA-N

InChi: InChI=1S/C19H35N3O7S/c1-2-4-23-6-8-25-10-11-27-13-15-29-17-19-30-18-16-28-14-12-26-9-7-24-5-3-21-22-20/h1H,3-19H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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