Cyclooctyne-O-PFP ester


Catalog No. Size PriceQuantity
M28701-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Cyclooctyne-O-PFP ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Product information

CAS Number: 886209-60-5

Molecular Weight: 348.26

Formula: C16H13F5O3

Chemical Name: 2,3,4,5,6-pentafluorophenyl 2-(cyclooct-2-yn-1-yloxy)acetate

Smiles: O=C(COC1CCCCCC#C1)OC1C(F)=C(F)C(F)=C(F)C=1F

InChiKey: FTKRNGMQMZGSDF-UHFFFAOYSA-N

InChi: InChI=1S/C16H13F5O3/c17-11-12(18)14(20)16(15(21)13(11)19)24-10(22)8-23-9-6-4-2-1-3-5-7-9/h9H,1-4,6,8H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 100 mg/mL (287.14 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Products are for research use only. Not for human use.

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