Complement C5-IN-1


Catalog No. Size PriceQuantity
M28750-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Complement C5-IN-1 (Compound 7) is a small-molecule inhibitor of complement component 5 protein (C5). Complement C5-IN-1 interacts with C5 to prevent its cleavage by the C5 convertase and blocks zymosan-induced the membrane-attack complex (MAC) deposition in 50% human whole blood with an IC50 of 0.77 µM.

Product information

CAS Number: 2365402-67-9

Molecular Weight: 444.52

Formula: C24H32N2O6

Chemical Name: 5-methoxy-2-({[(1S)-1-(2-methoxyphenyl)ethyl]carbamoyl}amino)-4-[(4-methylpentyl)oxy]benzoic acid

Smiles: CC(C)CCCOC1=CC(NC(=O)N[C@@H](C)C2=CC=CC=C2OC)=C(C=C1OC)C(O)=O

InChiKey: UFAFCKVYKJIJTR-INIZCTEOSA-N

InChi: InChI=1S/C24H32N2O6/c1-15(2)9-8-12-32-22-14-19(18(23(27)28)13-21(22)31-5)26-24(29)25-16(3)17-10-6-7-11-20(17)30-4/h6-7,10-11,13-16H,8-9,12H2,1-5H3,(H,27,28)(H2,25,26,29)/t16-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : ≥ 100 mg/mL (224.96 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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