Coumetarol


Catalog No. Size PriceQuantity
M28767-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Coumetarol (Dicumoxane) is a vitamin K antagonist.

Product information

CAS Number: 4366-18-1

Molecular Weight: 380.35

Formula: C21H16O7

Chemical Name: 4-hydroxy-3-[1-(4-hydroxy-2-oxo-2H-chromen-3-yl)-2-methoxyethyl]-2H-chromen-2-one

Smiles: COCC(C1C(=O)OC2=CC=CC=C2C=1O)C1C(=O)OC2=CC=CC=C2C=1O

InChiKey: BUCJFFQZPGTGPX-UHFFFAOYSA-N

InChi: InChI=1S/C21H16O7/c1-26-10-13(16-18(22)11-6-2-4-8-14(11)27-20(16)24)17-19(23)12-7-3-5-9-15(12)28-21(17)25/h2-9,13,22-23H,10H2,1H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Coumetarol (Dicumoxane), an oral anticoagulant, is active in both models. The vitamin K antagonist Coumetarol is effective in both models after oral treatment but inhibits the thrombus formation more strongly in the arterio-venous shunt model. Treatment with the vitamin K antagonist Coumetarol in a dose of 25 mg/kg p.o. twice daily for 2 days results in a significant reduction in thrombus weight by 50% in the venous stasis model and by 75% in the arterio-venous shunt model. In both experiments the coagulation time as measured by the Thrombotest is prolonged to the same extent.

Products are for research use only. Not for human use.

Payment & Security

PayPal Venmo

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

You may also like

Recently viewed