Cbl-b-IN-1


Catalog No. Size PriceQuantity
M28977-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Cbl-b-IN-1 (example 519) is a Cbl-b inhibitor, extracted from patent WO2019148005A1, with an IC50 <100 nM.

Product information

CAS Number: 2368841-84-1

Molecular Weight: 498.62

Formula: C29H34N6O2

Chemical Name: 4-({5-azaspiro[2.4]heptan-5-yl}methyl)-6-cyclopropyl-N-(3-{3-[(4-methyl-4H-1,2,4-triazol-3-yl)methyl]oxetan-3-yl}phenyl)pyridine-2-carboxamide

Smiles: CN1C=NN=C1CC1(COC1)C1C=C(C=CC=1)NC(=O)C1=CC(CN2CCC3(C2)CC3)=CC(=N1)C1CC1

InChiKey: VXMQSDNIOKDJHW-UHFFFAOYSA-N

InChi: InChI=1S/C29H34N6O2/c1-34-19-30-33-26(34)14-29(17-37-18-29)22-3-2-4-23(13-22)31-27(36)25-12-20(11-24(32-25)21-5-6-21)15-35-10-9-28(16-35)7-8-28/h2-4,11-13,19,21H,5-10,14-18H2,1H3,(H,31,36)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 60 mg/mL (120.33 mM; ultrasonic and warming and heat to 60°C).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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