Description
Boc-N-PEG2-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 302331-20-0
Molecular Weight: 283.34
Formula: C10H21NO6S
Chemical Name: tert-butyl N-{2-[2-(methanesulfonyloxy)ethoxy]ethyl}carbamate
Smiles: CC(C)(C)OC(=O)NCCOCCOS(C)(=O)=O
InChiKey: ZDLSZXWATPDDQS-UHFFFAOYSA-N
InChi: InChI=1S/C10H21NO6S/c1-10(2,3)17-9(12)11-5-6-15-7-8-16-18(4,13)14/h5-8H2,1-4H3,(H,11,12)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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