Bis-propargyl-PEG9


Catalog No. Size PriceQuantity
M29200-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Bis-propargyl-PEG9 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG9 can be used to synthesize the bivalent estrogen receptor ligands.

Product information

CAS Number: 1351373-47-1

Molecular Weight: 490.58

Formula: C24H42O10

Chemical Name: 4,7,10,13,16,19,22,25,28,31-decaoxatetratriaconta-1,33-diyne

Smiles: C#CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC#C

InChiKey: LGMGZRHYRPWDIM-UHFFFAOYSA-N

InChi: InChI=1S/C24H42O10/c1-3-5-25-7-9-27-11-13-29-15-17-31-19-21-33-23-24-34-22-20-32-18-16-30-14-12-28-10-8-26-6-4-2/h1-2H,5-24H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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