PF-03654746


Catalog No. Size PriceQuantity
M29248-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

PF-03654746 is a potent and selective histamine H3 receptor antagonist with high brain penetration.PF-03654746 reduces allergen-induced nasal symptoms, might be a novel therapeutic strategy to further explore allergic rhinitis.PF-03654746 improves cognitive efficacy and disease-modifying effects in Alzheimer's disease (AD).

Product information

CAS Number: 935840-31-6

Molecular Weight: 322.39

Formula: C18H24F2N2O

Chemical Name: N-ethyl-3-fluoro-3-{3-fluoro-4-[(pyrrolidin-1-yl)methyl]phenyl}cyclobutane-1-carboxamide

Smiles: CCNC(=O)C1CC(F)(C1)C1=CC(F)=C(CN2CCCC2)C=C1

InChiKey: SXMBKHYDZOCBMT-UHFFFAOYSA-N

InChi: InChI=1S/C18H24F2N2O/c1-2-21-17(23)14-10-18(20,11-14)15-6-5-13(16(19)9-15)12-22-7-3-4-8-22/h5-6,9,14H,2-4,7-8,10-12H2,1H3,(H,21,23)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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