DNA2 inhibitor C5


Catalog No. Size PriceQuantity
M29416-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

DNA2 inhibitor C5 is a potent, competitive and specific inhibitor of DNA2 nuclease activity with an IC50 of 20 μM. DNA2 inhibitor C5 inhibits nuclease, DNA dependent ATPase, helicase, and DNA binding activities of DNA2. DNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress.

Product information

CAS Number: 35973-25-2

Molecular Weight: 234.17

Formula: C10H6N2O5

Chemical Name: 8-nitro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

Smiles: [O-][N+](=O)C1=CC=CC2=C1NC=C(C(O)=O)C2=O

InChiKey: BMIZBCVEHSUUNO-UHFFFAOYSA-N

InChi: InChI=1S/C10H6N2O5/c13-9-5-2-1-3-7(12(16)17)8(5)11-4-6(9)10(14)15/h1-4H,(H,11,13)(H,14,15)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 31.25 mg/mL (133.45 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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