Description
SIRT1-IN-1 is a selective SIRT1 inhibitor with an IC50 of 0.205 μM. SIRT1-IN-1 inhibits SIRT2 with an IC50 of 11.5 μM. SIRT1-IN-1, a indole, is a cytomegalovirus (CMV) inhibitors and has antiviral activity.
Product information
CAS Number: 352554-02-0
Molecular Weight: 228.29
Formula: C14H16N2O
Chemical Name: 6-methyl-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide
Smiles: CC1=CC=C2NC3C(CCCC=3C2=C1)C(N)=O
InChiKey: KQWPYXBWZWLRMZ-UHFFFAOYSA-N
InChi: InChI=1S/C14H16N2O/c1-8-5-6-12-11(7-8)9-3-2-4-10(14(15)17)13(9)16-12/h5-7,10,16H,2-4H2,1H3,(H2,15,17)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 100 mg/mL (438.04 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
SIRT1-IN-1 (compound 2) has little effect on SIRT3 (IC50>100 μM) and HDAC (IC50>100 μM).
Products are for research use only. Not for human use.
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