GlyT1 Inhibitor 1


Catalog No. Size PriceQuantity
M30002-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

GlyT1 Inhibitor 1 is a potent and selective GlyT1 inhibitor with an IC50 of 38 nM for rGlyT1. Antipsychotic activity.

Product information

CAS Number: 1820934-93-7

Molecular Weight: 387.43

Formula: C22H21N5O2

Chemical Name: 3-[2-(2-methylpyridin-4-yl)-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-5-carbonyl]-4-(propan-2-yloxy)benzonitrile

Smiles: CC1=CC(=CC=N1)N1C=C2CN(CC2=N1)C(=O)C1=CC(=CC=C1OC(C)C)C#N

InChiKey: CIEHAYBWEMOJMN-UHFFFAOYSA-N

InChi: InChI=1S/C22H21N5O2/c1-14(2)29-21-5-4-16(10-23)9-19(21)22(28)26-11-17-12-27(25-20(17)13-26)18-6-7-24-15(3)8-18/h4-9,12,14H,11,13H2,1-3H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

GlyT1 Inhibitor 1 (Compound 46) demonstrates in vivo efficacy in a rat novel object recognition (NOR) assay after oral dosing at 0.1, 1, and 3 mg/kg.

Products are for research use only. Not for human use.

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