CI 972 anhydrous


Catalog No. Size PriceQuantity
M30092-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

CI 972 anhydrous is a potent, orally active, and competitive inhibitor of purine nucleoside phosphorylase (PNP) (Ki=0.83 μM) under development as a T cell-selective immunosuppressive agent.

Product information

CAS Number: 115787-68-3

Molecular Weight: 297.76

Formula: C11H12ClN5OS

Chemical Name: 2,6-diamino-7-[(thiophen-3-yl)methyl]-3H,4H,5H-pyrrolo[3,2-d]pyrimidin-4-one hydrochloride

Smiles: Cl.NC1NC2C(=O)NC(N)=NC=2C=1CC1=CSC=C1

InChiKey: SLNICZJKQXPOJA-UHFFFAOYSA-N

InChi: InChI=1S/C11H11N5OS.ClH/c12-9-6(3-5-1-2-18-4-5)7-8(14-9)10(17)16-11(13)15-7;/h1-2,4,14H,3,12H2,(H3,13,15,16,17);1H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

CI 972 anhydrous (5-150 mg/kg; p.o.) produces dose-dependent elevation of plasma inosine one hour after administration to rats.

Products are for research use only. Not for human use.

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