Description
Gastrazole (JB95008) is potent and selective CCK2/gastrin receptor antagonist. Gastrazole can decrease the level of gastric acid. Gastrazole inhibits the Gastrin-stimulated growth of pancreatic cancer.
Product information
CAS Number: 862583-15-1
Molecular Weight: 687.63
Formula: C34H32FN5Na2O7
Chemical Name: disodium 5-[(2S)-2-({6-[(cycloheptylmethyl)carbamoyl]-1H-1,3-benzodiazol-5-yl}formamido)-3-(2-fluorophenyl)propanamido]benzene-1,3-dicarboxylate
Smiles: [Na+].[Na+].[O-]C(=O)C1C=C(C=C(C=1)C([O-])=O)NC(=O)[C@H](CC1=CC=CC=C1F)NC(=O)C1C=C2N=CNC2=CC=1C(=O)NCC1CCCCCC1
InChiKey: VHAXHRARUCKASM-UJXPALLWSA-L
InChi: InChI=1S/C34H34FN5O7.2Na/c35-26-10-6-5-9-20(26)14-29(32(43)39-23-12-21(33(44)45)11-22(13-23)34(46)47)40-31(42)25-16-28-27(37-18-38-28)15-24(25)30(41)36-17-19-7-3-1-2-4-8-19;;/h5-6,9-13,15-16,18-19,29H,1-4,7-8,14,17H2,(H,36,41)(H,37,38)(H,39,43)(H,40,42)(H,44,45)(H,46,47);;/q;2*+1/p-2/t29-;;/m0../s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vivo:
Gastrazole (0.15-3 μmol/kg; i.v.) dose-dependently inhibits the Pentagastrin-stimulated gastric acid secretion.
Products are for research use only. Not for human use.
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