Dimetacrine


Catalog No. Size PriceQuantity
M30191-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Dimetacrine is a useful antidepressant effect, and can be used for the research of various types of depression.

Product information

CAS Number: 4757-55-5

Molecular Weight: 294.43

Formula: C20H26N2

Chemical Name: [3-(9,9-dimethyl-9,10-dihydroacridin-10-yl)propyl]dimethylamine

Smiles: CN(C)CCCN1C2=CC=CC=C2C(C)(C)C2=CC=CC=C12

InChiKey: RYQOGSFEJBUZBX-UHFFFAOYSA-N

InChi: InChI=1S/C20H26N2/c1-20(2)16-10-5-7-12-18(16)22(15-9-14-21(3)4)19-13-8-6-11-17(19)20/h5-8,10-13H,9,14-15H2,1-4H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

Dimetacrine is a useful antidepressant which can be used for the treatment of various types of depression. Dimetacrine in the highest concentration, 10 μM, decreases the contractile force to 36.5±9.1%. Dimetacrine, 0.3 μM, causes no statistically significant decline in contractile force from the controls. Tachycardia is observed after the administration of Dimetacrine, 1 to 3 mg/kg i.v., and the maximum response is obtained in dose of 3 mg/kg i.v.. The administration of Dimetacrine, 30 mg/kg i.v., causes an abrupt fall in blood pressure with tachycardia or bradycardia followed by cardiac arrest. Respiratory rate increases 40 min after the onset of infusion of Dimetacrine. Arterial blood pressure falls 50 min after the onset of infusion of Dimetacrine.

Products are for research use only. Not for human use.

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