Polaprezinc


Catalog No. Size PriceQuantity
M30234-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Polaprezinc is an orally bioavailable chelate composed of zinc and L-carnosine, with potential gastroprotective, anti-oxidant, anti-ulcer and anti-inflammatory activities.

Product information

CAS Number: 107667-60-7

Molecular Weight: 290.63

Formula: C9H13N4O3Zn

Chemical Name: (3-aminopropanoyl)[(1S)-1-carboxy-2-(1H-imidazol-5-yl)ethyl]azanide zinc

Smiles: [Zn].NCCC(=O)[N-][C@@H](CC1=CN=CN1)C(O)=O

InChiKey: GFWBKUDRXMQSFD-FJXQXJEOSA-M

InChi: InChI=1S/C9H14N4O3.Zn/c10-2-1-8(14)13-7(9(15)16)3-6-4-11-5-12-6;/h4-5,7H,1-3,10H2,(H3,11,12,13,14,15,16);/p-1/t7-;/m0./s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : < 1 mg/mL (insoluble or slightly soluble). H2O : 3.37 mg/mL (11.68 mM; ultrasonic and warming and adjust pH to 1-2 with HCl).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

Polaprezinc (PZ) is an antiulcer drug and a chelating compound consisting of a zinc ion, L-carnosine, a β-alanine dipeptide and L-histidine. Polaprezinc exerts antioxidant effects and scavenges free radicals. The efficacy of Polaprezinc is reported for acute radiation proctitis in an animal model and demonstrates that Polaprezinc has an anti-inflammatory effect following exposure to radiation.

Products are for research use only. Not for human use.

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