RGH-5526


Catalog No. Size PriceQuantity
M30252-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

RGH-5526 (GYKI-11679) is a new antihypertensive agent.

Product information

CAS Number: 69579-13-1

Molecular Weight: 335.40

Formula: C16H25N5O3

Chemical Name: tert-butyl (3E)-3-{2-[6-(morpholin-4-yl)pyridazin-3-yl]hydrazin-1-ylidene}butanoate

Smiles: C/C(/CC(=O)OC(C)(C)C)=N\NC1=CC=C(N=N1)N1CCOCC1

InChiKey: YCVVCSICMNKDBE-SFQUDFHCSA-N

InChi: InChI=1S/C16H25N5O3/c1-12(11-15(22)24-16(2,3)4)17-18-13-5-6-14(20-19-13)21-7-9-23-10-8-21/h5-6H,7-11H2,1-4H3,(H,18,19)/b17-12+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

RGH-5526 (GYKI-11679) is a new antihypertensive agent. Results show a sharp (61%) reduction in the hypothalamic Noradrenaline (NA) level 2 h after the administration of 10 mg/kg of RGH-5526, and this effect lasts for 4 to 6 h. It is demonstrated that RGH-5526 exerts a greater NA lowering effect in the hypothalamus than in the periphery. RGH-5526 does not influence the hypothalamic monoamine oxidase (MAO)-activity following prolonged treatment.

Products are for research use only. Not for human use.

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