Description
Glycolic acid oxidase inhibitor 1 is a glycolate oxidase inhibitor, extracted from patent EP0021228A1, in Table IV.
Product information
CAS Number: 77529-42-1
Molecular Weight: 344.16
Formula: C16H10BrNO3
Chemical Name: 3-{4'-bromo-[1,1'-biphenyl]-4-yl}-4-hydroxy-2,5-dihydro-1H-pyrrole-2,5-dione
Smiles: OC1=C(C2C=CC(=CC=2)C2C=CC(Br)=CC=2)C(=O)NC1=O
InChiKey: WMLWRZOUOGMDNS-UHFFFAOYSA-N
InChi: InChI=1S/C16H10BrNO3/c17-12-7-5-10(6-8-12)9-1-3-11(4-2-9)13-14(19)16(21)18-15(13)20/h1-8H,(H2,18,19,20,21)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : ≥ 137 mg/mL (398.07 mM).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vivo:
Glycolic acid oxidase inhibitor 1 inhibits oxalate biosynthesis in isolated perfused rat liver. Glycolate oxidase inhibitors provide a specific approach to the prevention and treatment of calcium oxalate renal lithiasis.
Products are for research use only. Not for human use.
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