Bidisomide


Catalog No. Size PriceQuantity
M30287-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Bidisomide (SC40230) is a class I antiarrhythmic agent.

Product information

CAS Number: 116078-65-0

Molecular Weight: 407.98

Formula: C22H34ClN3O2

Chemical Name: 2-(2-chlorophenyl)-4-(piperidin-1-yl)-2-{2-[N-(propan-2-yl)acetamido]ethyl}butanamide

Smiles: CC(=O)N(CCC(CCN1CCCCC1)(C1=CC=CC=C1Cl)C(N)=O)C(C)C

InChiKey: GTEPPJFJSNSNIH-UHFFFAOYSA-N

InChi: InChI=1S/C22H34ClN3O2/c1-17(2)26(18(3)27)16-12-22(21(24)28,19-9-5-6-10-20(19)23)11-15-25-13-7-4-8-14-25/h5-6,9-10,17H,4,7-8,11-16H2,1-3H3,(H2,24,28)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

The antiarrhythmic effects of Bidisomide, a new class I antiarrhythmic drug is investigated in early-phase ventricular arrhythmias induced by coronary artery occlusion and reperfusion in anesthetized rats. Bidisomide (5 mg/kg) reduces the number of premature ventricular complexes and the incidence of ventricular tachycardia and ventricular fibrillation similarly to Mexiletine (MXT) and Disopyramide (DSP) in rats with ventricular arrhythmias induced by coronary artery occlusion. In rats with ventricular arrhythmias induced by coronary artery reperfusion following a 5 min coronary occlusion, the antiarrhythmic effects of 5 mg/kg of Bidisomide are similar to those of the same doses of MXT and DSP. All three drugs significantly slow the heart rate.

Products are for research use only. Not for human use.

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