(+)-Coclaurine


Catalog No. Size PriceQuantity
M30296-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

(+)-Coclaurine ((+)-(R)-Coclaurine), benzyltetrahydroisoquinoline alkaloid isolated from a variety of plant sources. (+)-Coclaurine has anti-aging activity.

Product information

CAS Number: 2196-60-3

Molecular Weight: 285.34

Formula: C17H19NO3

Chemical Name: (1R)-1-[(4-hydroxyphenyl)methyl]-6-methoxy-1,2,3,4-tetrahydroisoquinolin-7-ol

Smiles: COC1=CC2CCN[C@H](CC3C=CC(O)=CC=3)C=2C=C1O

InChiKey: LVVKXRQZSRUVPY-OAHLLOKOSA-N

InChi: InChI=1S/C17H19NO3/c1-21-17-9-12-6-7-18-15(14(12)10-16(17)20)8-11-2-4-13(19)5-3-11/h2-5,9-10,15,18-20H,6-8H2,1H3/t15-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

An intracerebroventricular injection of (+)-Coclaurine (d-Coclaurine; 50 μg) produces a slight increase in 3,4-dihydroxyphenylacetic acid level and a significant increase in homovanillic acid level in the mouse striatum. (+)-Coclaurine blocks postsynaptic but not presynaptic dopamine receptors in the mouse striatum.

Products are for research use only. Not for human use.

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