HS79


Catalog No. Size PriceQuantity
M30342-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

HS-79 is an enantiomer of Fasnall, which is a selective fatty acid synthase (FASN) inhibitor. HS-79 is able to inhibit the incorporation of tritiated acetate into lipids with an IC50 of 1.57 μM.

Product information

CAS Number: 2138838-56-7

Molecular Weight: 338.47

Formula: C19H22N4S

Chemical Name: (3R)-1-benzyl-N-{5,6-dimethylthieno[2,3-d]pyrimidin-4-yl}pyrrolidin-3-amine

Smiles: CC1C2=C(N[C@H]3CN(CC4C=CC=CC=4)CC3)N=CN=C2SC=1C

InChiKey: VSXRMURGJRAOCU-MRXNPFEDSA-N

InChi: InChI=1S/C19H22N4S/c1-13-14(2)24-19-17(13)18(20-12-21-19)22-16-8-9-23(11-16)10-15-6-4-3-5-7-15/h3-7,12,16H,8-11H2,1-2H3,(H,20,21,22)/t16-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Fasnall, a thiophenopyrimidine selectively targeting FASN through its co-factor binding sites. Fasnall has anti-proliferative activity and induces apoptosis in breast cancer cells.

Products are for research use only. Not for human use.

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