Description
Azido-PEG8-CH2COO-PFP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 2182601-80-3
Molecular Weight: 619.53
Formula: C24H34F5N3O10
Chemical Name: 2,3,4,5,6-pentafluorophenyl 26-azido-3,6,9,12,15,18,21,24-octaoxahexacosanoate
Smiles: [N-]=[N+]=NCCOCCOCCOCCOCCOCCOCCOCCOCC(=O)OC1C(F)=C(F)C(F)=C(F)C=1F
InChiKey: JAGMBOXHJXUFJS-UHFFFAOYSA-N
InChi: InChI=1S/C24H34F5N3O10/c25-19-20(26)22(28)24(23(29)21(19)27)42-18(33)17-41-16-15-40-14-13-39-12-11-38-10-9-37-8-7-36-6-5-35-4-3-34-2-1-31-32-30/h1-17H2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 100 mg/mL (161.41 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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